That is not to say you should not go ahead; these small improvements tend to accumulate. I do, however, think that one should do some due diligence (and do some math) to avoid being disappointed due to excessive expectations.
For example, you don't *need* Zemok. He is nice to have, but not a world better than a doff-less APBx2 build.
Or weapon mods: there is a world of difference in the prices of a crtidx2/crith/pen weapon and a critdx3/pen...but the actual dps difference between the two is less than 2% on that weapon's weapon damage output.